Lxxxviii. Dismutation of Pyruvic Acid in Gonococcus and Staphylococcus by Hans
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چکیده
THE literature on bacterial metabolism contains references which suggest that the anaerobic dismutation of pyruvic acid which we have shown to occur in animal tissues (see the preceding paper) may also take place in certain bacteria. Barron et al. [1932; 1933; 1934; 1936], for instance, described experiments concerning the oxidation of pyruvic acid in Gonococcus and showed that there is a specific mechanism by which pyruvic acid is oxidized to form acetic acid and carbon dioxide. He assumed that this oxidation is directly effected by molecular oxygen and he named the enzymic system concerned "ac-ketonoxidase". His data, however, also allow the assumption that the oxidation of pyruvic acid is brought about by the same type of dismutation which occurs in animal tissues:
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Studies on Biological Oxidations
Pyruvic acid is one of the most reactive substances among those of importance in cellular metabolism. When carbohydrate is split during fermentation, pyruvic acid is the main end-product of the resulting series of phosphorylated oxidation-reductions. It thus becomes the immediate source for the formation of both lactic acid and alcohol. Pyruvic acid is decarboxylated by yeast; it may react with...
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